Sophora japonica extracts accelerates keratinocyte differentiation through miR-181a
نویسندگان
چکیده
منابع مشابه
Sophora japonica extracts accelerates keratinocyte differentiation through miR-181a
Background: The Sophora japonica extracts contain flavonol triglycoside, isoflavonol, coumarone chromone, saponin, triterpene glucoside, phospholipids, alkaloids, amino acids, polysaccharides, and fatty acids. These components have physiological effects such as anti-infertility and anti-cancer activities. This study investigated the regulation of keratinocyte differentiation upon treatment with...
متن کاملGalectin-7 regulates keratinocyte proliferation and differentiation through JNK-miR-203-p63 signaling
Galectin-7, a member of the β-galactoside-binding protein family, is primarily expressed in stratified epithelial cells, including keratinocytes. There is information in the literature suggesting a role for this protein in regulation of keratinocyte survival and growth, but the underlying mechanism remains relatively unknown. Moreover, its expression pattern in the epidermis suggests that it is...
متن کاملH19 lncRNA regulates keratinocyte differentiation by targeting miR-130b-3p
Aberrant differentiation of keratinocytes has been demonstrated to be associated with a number of skin diseases. A growing number of studies have showed that long noncoding RNAs (lncRNAs) have an important part in gene regulation, however, the role of lncRNAs in keratinocyte differentiation remains to be largely unknown. In the present study, we demonstrated that lncRNA-H19 act as an endogenous...
متن کاملComparison of Staining by Sophora japonica L. and Phellodendron
Sophora japonica L. of 10-20 m tall is a popular ornamental tree in Europe, North America and South Africa, grown for its white flowers, borne in late summer after most other flowering trees have long finished flowering. Phellodendron amurense Ruprecht commonly called the Amur cork tree is a major source of huáng bò used in traditional Chinese medicine as a painkiller. In this study, staining p...
متن کاملIsolation of Antiosteoporotic Compounds from Seeds of Sophora japonica
Chemical investigation of Sophora japonica seeds resulted in the isolation of seven metabolites identified as: genistin (1), sophoricoside (2), sophorabioside (3), sophoraflavonoloside (4), genistein 7,4'-di-O-β-D-glucopyransoide (5), kaempferol 3-O-α-L-rhamnopyranosyl(1 → 6)β-D-glucopyranosyl(1 → 2)β-D-glucopyranoside (6) and rutin (7). Compounds 1, 2 and 5 showed significant estrogenic prolif...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biomedical Dermatology
سال: 2018
ISSN: 2398-8460
DOI: 10.1186/s41702-017-0011-6